![]() Light microscopy images of hepatocytes labeled with (a)0.96-, (b)1.63-, (c)2.79-, (d)4.50-, and (e)5.80-&$181m particles. Cark perinuclear spheres are individual MPIOs. Partcle numbers per cell ranged from several hundred for the smaller particles to tens for the largest particles. d and e: Thirty -five 4.5-&$181m and 17 5.8-&$181m particles, yielding iron contents of ~387 and 75 pg iron, respectively. Erik M. Shapiro, Sizing It Up: Cellular MRI Using Micron-Sized Iron Oxide Particles, Magnetic Resonance in Medicine 53:329-338(2005) |