Personal Information
Hellmut Merkle
Staff Scientist
NIH, NINDS, LFMI-10 Center Drive
Bldg. 10, Rm. B1D727, MSC 1065
Bethesda, MD 20892-1065
Phone: (301)594-7306
FAX: (301)480-2558
Email: merkleh at ninds.nih.gov 		Personal photo is missing

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Recent Publications

Recent Publications in LFMI
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  1. J.B. Goense, S. Ku, H. Merkle, A.S. Tolias, N.K. Logothetis
    fMRI of the temporal lobe of the awake monkey at 7 T, NeuroImage 39: 1081-1093(2008)
    2. Link to PubMed
  2. K. Chuang, P. van Gelderen, H. Merkle, J. Bodurka, V.N. Ikonomidou, A.P. Koretsky, J.H. Duyn, L.S. Talagala
    Mapping resting-state functional connectivity using perfusion MRI, NeuroImage 40: 1595-1605(2008)
    3. Link to PubMed
  3. A.C. Zappe, J. Pfeuffer, H. Merkle, N.K. Logothetis, J.B. Goense
    The effect of labeling parameters on perfusion-based fMRI in nonhuman primates, Journal of Cerebral Blood Flow and Metabolism 28: 640-652(2008)
    4. Link to PubMed
  4. J. Pfeuffer, A. Shmuel, G.A. Keliris, T. Steudel, H. Merkle, N.K. Logothetis
    Functional MR imaging in the awake monkey: effects of motion on dynamic off-resonance and processing strategies, Journal of Magnetic Resonance Imaging 25: 869-882(2007)
    5. Link to PubMed
  5. I. Choi, S. Lee, M. Garwood, K. Ugurbil, H. Merkle
    Simple Partial Volume Transceive Coils for Homonuclear in vivo Human Brain studies at high magnetic fields, Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering 31: 71-85(2007)
  6. S.D. Keilholz, A.C. Silva, M. Raman, H. Merkle, A.P. Koretsky
    BOLD and CBV-weighted functional magnetic resonance imaging of the rat somatosensory system, Magnetic Resonance in Medicine 55: 316-324(2006)
    7. Link to PubMed
  7. T. Li, P. van Gelderen, H. Merkle, L.S. Talagala, A.P. Koretsky, J.H. Duyn
    Extensive heterogeneity in white matter intensity in high-resolution T2*-weighted MRI of the human brain at 7.0 T, NeuroImage 32: 1032-1040(2006)
    8. Link to PubMed
  8. I. Choi, S. Lee, H. Merkle, J. Shen
    In vivo detection of gray and white matter differences in GABA concentration in the human brain, NeuroImage 33: 85-93(2006)
    9. Link to PubMed
  9. J. Lee, A.C. Silva, H. Merkle, A.P. Koretsky
    Manganese-enhanced magnetic resonance imaging of mouse brain after systemic administration of MnCl2: dose-dependent and temporal evolution of T1 contrast, Magnetic Resonance in Medicine 53: 640-648(2005)
    10. Link to PubMed
  10. W. Driesel, H. Merkle, S. Hetzer, S. Zysset, H.E. Moeller
    Reengineered helmut coil for human brain studies at 3T, MRE 27B 1: 64-74(2005)
  11. I. Choi, S. Lee, H. Merkle, J. Shen
    A single-shot, two-echo technique for simultaneous measurement of GABA and creatine in the human brain in vivo, Magnetic Resonance in Medicine 51: 1115-1121(2004)
    12. Link to PubMed
  12. J. Pfeuffer, H. Merkle, M. Bayerlein, T. Steudel, N.K. Logothetis
    Anatomical and functional MR imaging in the macaque monkey using a vertical large-bore 7 tesla setup, MRI 22: 1343-1359(2004)
  13. S.D. Keilholz, A.C. Silva, M. Raman, H. Merkle, A.P. Koretsky
    Functional MRI of the rodent somatosensory pathway using multislice echo planar imaging, Magnetic Resonance in Medicine 52: 89-99(2004)
    14. Link to PubMed
  14. J. Pfeuffer, C. Juchem, H. Merkle, A. Nauert, N.K. Logothetis
    High-field localized 1H 2D MR spectroscopy in the anesthezied and in the awake monkey, MRI 22: 1361-1372(2004)
  15. C. Juchem, H. Merkle, G.S. Sobering, N.K. Logothetis, J. Pfeuffer
    Region and volume dependencies in spectral linewidth assessed by 1H MR chemical shift imaging in the monkey brain at 7T, MRI 22: 1373-1383(2004)
  16. A.C. Silva, H. Merkle
    Hardware considerations for functional magnetic resonance imaging, Concepts in Magnetic Resonance Part A: Magnetic Resonance Engineering 16: 35-49(2003)
  17. X. Zhang, X. Zhu, R. Tian, Y. Zhang, H. Merkle, W. Chen
    Measurement of arterial input function of 17O water tracer in rat carotid artery by using a region-defined (REDE) implanted vascular RF coil, MAGMA 16: 77-85(2003)
  18. X. Zhu, Y. Zhang, R. Tian, H. Lei, N. Zhang, X. Zhang, H. Merkle, K. Ugurbil, W. Chen
    Development of 17O NMR approach for fast imaging of cerebral metabolic rate oxygen in rat brain at high field, Proc. Natl. Acad. Sci. 99: 13194-13199(2002)
  19. C. Collins, Q. Yang, J. Wang, X. Zhang, H. Lui, S. Michaeli, X. Zhu, G. Adriany, J. Vaughan, P. Andersen, H. Merkle, K. Ugurbil, M. Smith, W. Chen
    Different excitation and reception distribution with a single loop transmit-receive surface coil near a head-sized spherical phantom at 300 MHz, Magnetic Resonance in Medicine 47: 1026-1028(2002)
  20. P. Bolan, L. Delabarre, E. Baker, H. Merkle, L. Everson, D. Yee, M. Garwood
    Eliminating spurious lipid sidebands in 1H spectra in breast lesions, Magnetic Resonance in Medicine 48: 215-222(2002)
  21. T. Duong, E. Tacoub, G. Adriany, X. Hu, K. Ugurbil, J. Vaughan, H. Merkle, S. Kim
    High-resolution, spin-echo BOLD and CBF fMRI at 4 and 7 T, Magnetic Resonance in Medicine 48: 589-593(2002)
  22. I. Tkac, P. Andersen, G. Adriany, H. Merkle, K. Ugurbil, R. Gruetter
    In vivo 1H NMR spectroscopy of the human brain at 7T, Magnetic Resonance in Medicine 46: 451-456(2002)
  23. R. Bartha, H. Merkle, P. Andersen, W. Chen, K. Ugurbil, M. Garwood
    In-vivo T2+ measurement in the human occipital lobe at 4T and 7T by carr-purcell MR imaging: detection of microscopic susceptibility contrast, Magnetic Resonance in Medicine 47: 742-750(2002)
  24. S. Michaeli, M. Garwood, X. Zhu, L. Delabarre, P. Andersen, G. Adriany, H. Merkle, K. Ugurbil, W. Chen
    Proton T2 relaxation study of water, N-acetylaspartate, and creatine in human brain using hahn and carr-purcell spin echoes at 4T and 7T, Magnetic Resonance in Medicine 47: 629-633(2002)
  25. N.K. Logothetis, H. Merkle, M. Augath, T. Trinath, K. Ugurbil
    Ultra-high resolution fmRI in monkeys with implanted RF coils, Neuron 35: 227-242(2002)
  26. J. Pfeuffer, P. Van de moortelle, E. Yacoub, G. Adriany, P. Andersen, H. Merkle, M. Garwood, K. Ugurbil, X. Hu
    Zoomed functional imaging in the human brain at 7 Tesla with simultaneously high spatial and temporal resolution, NeuroImage 17: 272-286(2002)
  27. X. Zhu, H. Merkle, K. Ugurbil, W. Chen
    17O Relaxation time and NMR sensitivity of cerebral water and their field dependence, Magnetic Resonance in Medicine 45: 543-549(2001)
  28. J. Vaughan, M. Garwood, C. Collins, W. Liu, L. Delabarre, G. Adriany, P. Andersen, H. Merkle, R. Goebel, M. Smith, K. Ugurbil
    7T vs. 4T: RF power, hemogeneity, & signal-to-noise comparison in head images, Magnetic Resonance in Medicine 46: -(2001)
  29. E. Yacoub, A. Shmuel, J. Pfeuffer, P. Van de moortelle, G. Adriany, P. Andersen, J. Vaughan, H. Merkle, K. Ugurbil, X. Hu
    Imaging brain function in humans at 7 tesla, Magnetic Resonance in Medicine 45: 588-594(2001)
  30. K. Ugurbil, D. Kim, T. Duong, X. Hu, S. Ogawa, R. Gruetter, W. Chen, S. Kim, X. Zhu, E. Yacoub, P. Van de moortelle, A. Shmuel, J. Pfeuffer, H. Merkle, P. Andersen, G. Adriany
    Magnetic resonance imaging of brain function and neurochemistry, Proceedings of the IEEE 89: -(2001)
  31. Y. Cho, H. Merkle, Y. Zhang, N. Tsekos, R. Bache, K. Ugurbil
    Noninvasive measurements of transmural myocardial metabolites using 3-D 31P NMR spectroscopy, Am J Heart Circ Physiol 280: H489-H497(2001)

 

 
 
 
 
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